Book Chapter

Harnessing the Toxocara Genome to Underpin Toxocariasis Research and New Interventions

RB Gasser, PK Korhonen, XQ Zhu, ND Young

ADVANCES IN PARASITOLOGY, VOL 91 | Advances in Parasitology | ELSEVIER ACADEMIC PRESS INC | Published : 2016

DOI: 10.1016/bs.apar.2015.12.001

Abstract

Parasitic worms, such as flatworms (platyhelminths) and roundworms (nematodes), cause substantial morbidity and mortality in animals and people globally. The ascaridoid nematode Toxocara canis is a zoonotic parasite of socioeconomic significance worldwide. In humans, this worm causes toxocariasis (disease) mainly in underprivileged communities in both the developed and developing worlds. While reasonably well studied from clinical and epidemiological perspectives, little is understood about the molecular biology of T. canis, its relationship with its hosts and the disease that it causes. However, a recent report of the draft genome and transcriptomes of T. canis should underpin many fundamen..

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Keywords

Genome
3009 Veterinary Sciences
Gene-Expression
Control
Toxascaris-Leonina
Adult Ascaris-Suum
Parasitic Nematodes
Mitochondrial Genomes
Ribosomal Dna
Infection
Bioinformatics
Parasite–host Interactions
Science & Technology
Treatment
Life Sciences & Biomedicine
Internal Transcribed Spacers
30 Agricultural, Veterinary and Food Sciences
3 Good Health and Well Being
Infectious Diseases
Diagnosis
Genetics
Molecular Biology
C-Type Lectin
Diagnostic Morphology
Infective Larval Stage
2.2 Factors Relating To the Physical Environment
Parasitology